Leucocyte alkaline phosphatase in neonatal infections.

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Leucocyte alkaline phosphatase in neonatal infections SUBHASH

Introduction Interest in the activity of alkaline phosphatase of human leucocytes has grown rapidly with the increasing number of reports demonstrating significant shifts of activity in different clinical states. Leucocyte alkaline phosphatase (LAP), determined by cytochemical methods, is increased in bacterial infections of the adult, but to the best of the author's knowledge, there are no dat...

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Leucocyte alkaline phosphatase in neonatal infections.

The leucocyte alkaline phosphatase (LAP) score was estimated in healthy and infected neonates. A leucocyte band count was also done simultaneously. The infected group showed a significant (P < 0.001) decrease in the LAP score and a significant (P < 0.001) increase in the band count. These findings are discussed.

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Leucocyte Alkaline Phosphatase in Klinefelter's Syndrome.

A rise in the level of leucocyte alkaline phosphatase (LAP) has recently been reported in mongolism (Trubowitz, Kinnan, and Masek, I962; Lennox, White, and Campbell, I962; King, Gillis, and Baikie, I962; Alter, Lee, Pourfar, and Dobkin, I963; O'Sullivan and Pryles, I963), and it has been suggested that this might be the direct effect of a gene situated on the chromosome which is present in trip...

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Altered isozyme patterns of leucocyte alkaline phosphatase in disease states.

Leucocyte alkaline phosphatase (LAP) is a granulocyte enzyme whose concentration varies in disease states. In order to determine whether the pattern of expression is altered in leukaemic granulocytes, we have analysed the LAP isozyme pattern of a series of normal subjects and patients with various haematological diseases. Electrophoretic patterns of partially purified LAP samples were determine...

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Cord Blood Alkaline Phosphatase as an Indicator of Neonatal Jaundice

BACKGROUND Management of hyperbilirubinemia remains a challenge for neonatal medicine because of the risk of neurological complications related to the toxicity of severe hyperbilirubinemia. OBJECTIVES The purpose of this study was to examine the validity of cord blood alkaline phosphatase level for predicting neonatal hyperbilirubinemia. PATIENTS AND METHODS Between October and December 201...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1980

ISSN: 0032-5473

DOI: 10.1136/pgmj.56.657.485